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Brown fat (black) shows up in a PET-CT scan of a man after exposure to cold (right) but is not as apparent in a scan at room temperature (left). |
W. Van Marken Lichtenbelt |
The human body hides more than one
kind of fat. White fat cells, which we usually think of when we think of fat,
store energy. But brown fat is different: Its a type of fat that burns energy
and gives off heat.
When you were born, you had a pad
of brown fat on your back, and it helped you control your body temperature.
Mice also have brown fat on their backs. Until now, scientists suspected human
adults dont have brown fat or if they do, the brown fat is not important.
Three recent studies show that
human adults do have brown fat, and it may be important for controlling body
weight. And unlike babies, adults store brown fat in the neck, abdomen, above
the collarbone and along the spine.
In the first study, researcher Ronald Kahn of the Joslin Diabetes Center and Harvard Medical School
in Boston looked at the medical records of nearly 2,000 people who had received a PET-CT scan. To get a PET, or
positron emission tomography, scan, a person is injected with a chemical that
emits particles called positrons. Inside the persons body, these positrons
create radiation called gamma rays, which pass through the body and are
detected by special machines outside the body. This type of scan provides a three-dimensional
picture of whats going on inside the body. PET scans are often used to
diagnose cancer. A CT scan uses
X-rays to see inside a body.
Kahn and his team found brown fat
in the scans of 3.1 percent of the men studied and 7.5 percent of the women.
People younger than 50 and lean people were more likely to have brown fat.
It is now without dispute that
brown fat is present in adult humans, Kahn says.
When the researchers checked the
scans against the weather records, they found that brown fat was more likely to
show up when the temperature outside was cold. This comparison suggests brown
fat burns more energy in colder temperatures.
The connection between brown fat
and temperature was explored in the second study. Dutch researchers took scans
of lean and overweight men at two temperatures, 72 degrees Fahrenheit (room
temperature) and 61 degrees Fahrenheit. At the higher temperature, brown fat
barely appeared on the scans. But when the temperature dropped, brown fat
appeared on the scans of the leaner men. The more overweight the man, the less
brown fat appeared. The third study, conducted by Swedish scientists, also
found evidence of brown fat in adults.
These studies suggest that brown
fat may burn more energy in people who are lean. The connection between brown
fat and being overweight is less clear. Scientists wonder: Does having less
brown fat cause a person to become overweight, or does being overweight reduce
the amount of brown fat in a person?
In other words, overweight people
may be overweight partially because they dont have enough brown fat to help burn
energy. On the other hand, their excessive amount of white fat may keep the
brown fat from burning energy.
Power words: (from Britannica.com and the Yahoo! Kids Dictionary)
PET scan: Positron emission tomography, an imaging
technique used in medical diagnosis and biomedical
research. It has proved particularly useful for studying brain and heart
functions, as well as diagnosing cancer.
CT scan: Imaging method that uses a low-dose beam
of X-rays that crosses the body at many different angles.
Brown fat: A dark-colored tissue in many mammals that generates
heat to regulate body temperature, especially in hibernating animals.